In the 21st century, Slough has seen major redevelopment in the town centre. Old buildings are being replaced with new offices and shopping complexes. Tesco has replaced an existing superstore with a larger Tesco Extra. The Heart of Slough Project is a plan for the large-scale redevelopment of the town centre as a focus and cultural quarter for the creative media, information and communications industries. It will create a mixed-use complex, multi-functional buildings, visual landmarks and a public space in the Thames Valley. Recommendations for the £400 million project have been approved, and planning approval was given by Slough Borough Council’s planning committee on 9 July 2009. Work began in 2010 for completion in 2018.

In December 2009, two key components of the project were signed: the Homes and Communities Agency (HCA) signed its agreement to provide £11m of funding for infrastructure, and Thames Valley University (TVU) courses which are due to remain in the town have found a new home at The Centre in Farnham Road, Slough. In parallel to the town centre redevelopment plan, SEGRO (owner of the Slough Trading Estate) plans to spend £600 million over the next 20 years on the trading estate. This is intended to create environmentally sustainable buildings, open green spaces, two hotels, a conference centre, cafés, restaurants, and better transport facilities to improve links to Slough town centre and the surrounding residential areas. It is claimed that the plan will create more than 4,100 new jobs and contribute around £100m a year to Slough’s economy. If both plans go ahead in their current forms, nearly £1 billion will be spent on redeveloping Slough over the next 20 years.

Herschel Park (known as Upton Park until 1949) is currently being relandscaped in a multi-million pound effort to bring it back to its former Victorian era glory. The park was featured in an episode of the documentary programme ‘Who Do You Think You Are?‘ focusing on the TV presenter Davina McCall.

£2 million has been set aside to improve disabled access to Slough railway station in preparation for an expected increase in use during the 2012 London Olympics. Final preparations are under way for the regeneration of the Britwell suburb of Slough. The multi-million pound upgrade will involve tearing down a dilapidated block of flats in Wentworth Avenue and replacing them with new homes, as well as relocating the shopping parade in the street to nearby Kennedy Park. As part of the Heart of Slough project, construction work on a new bus station began in March 2010 following weeks of demolition work to half of the existing bus station and the removal of Compair House near the railway station; it is expected to be completed by January 2011.

Redevelopment on this scale has been strongly criticised by conservation groups. The Twentieth Century Society has stated that “[A] tragically high quantity of good buildings have been demolished in Slough in recent years, including grand Art-Deco-styled factories by the likes of Wallis Gilbert and high-quality post-war offices. More are to come down as the town tries to erase its past and reinvent itself from scratch. Despite famously heckling Slough, John Betjeman‘s praise for the Town Hall’s architecture as ‘a striving for unity out of chaos’ in 1948 has never been so relevant as today. C20 believes that the redevelopment of the Town Hall would be an act of vandalism to the civic centre and is supporting the Campaign to Save Slough’s Heritage in their request for a review of the decision.”